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Possible role of insulin in the transport of tyrosine and tryptophan from blood to brain

Authors :
Gian Luigi Gessa
Pier Luigi Onali
Alessandro Tagliamonte
Maria C. Olianas
M. G. DeMontis
Source :
Pharmacological Research Communications. 7:493-499
Publication Year :
1975
Publisher :
Elsevier BV, 1975.

Abstract

The administration of insulin or the ingestion of glucose increases the concentration of tryptophan and tyrosine in the brain. This increase is associated with a parallel decrease in the concentration of free tryptophan and tyrosine in serum. The results suggest that insulin enhances the transport of tyrosine and tryptophan from blood to brain.

Details

ISSN :
00316989
Volume :
7
Database :
OpenAIRE
Journal :
Pharmacological Research Communications
Accession number :
edsair.doi...........584aef0014f53240965745e22037d515
Full Text :
https://doi.org/10.1016/0031-6989(75)90010-7