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Effect of Isolation Stress on Glucose/Lipid Metabolism in Spontaneously Diabetic Torii (SDT) Fatty Rats
- Source :
- British Journal of Medicine and Medical Research. 8:588-594
- Publication Year :
- 2015
- Publisher :
- Sciencedomain International, 2015.
-
Abstract
- Aim: The Spontaneously Diabetic Torii (SDT) fatty rat is a novel obese type 2 dia betic model, showing hyperphagia, obesity, and diabetes mellitus from a young age. In this study, we investigated the effects of isolation stress on pathophysiology in SDT fatty rats. Methods: SDT fatty rats (4 weeks old) were housed 3 per cage for 2 weeks and separated as males or females so as each gender will be placed in a separate cage to avoid mating. After acclimatization in 6 weeks of age, the rats were exposed to isolation stress (IS) (one rat per cage, using 5 animals in each sex). In the control group, each sex of experimental rats were housed
- Subjects :
- medicine.medical_specialty
Environmental Engineering
business.industry
Cholesterol
Blood sugar
Lipid metabolism
medicine.disease
Acclimatization
Obesity
Industrial and Manufacturing Engineering
Pathophysiology
chemistry.chemical_compound
Endocrinology
chemistry
Internal medicine
Diabetes mellitus
Medicine
Histopathology
business
Subjects
Details
- ISSN :
- 22310614
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- British Journal of Medicine and Medical Research
- Accession number :
- edsair.doi...........58468f22f0e7c4243c20c1e6ba18c839