ChemInform Abstract: Synthesis and Evaluation of Cytotoxic Activity of Novel Arylsulfonylimidazolidinones

Authors :: Hyun Soo Lee
Chong-Ock Lee
Jae-Shin Song
Sang-Hun Jung
Sang Un Choi
Source :: ChemInform. 28
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: Synthesis of novel arylsulfonylimidazolidinones 3 and 4 containing sulfonylurea pharmacophore and evaluation of their in vitro cytotoxicity against human cell lines were investigated. As a result, a series of 4-phenyl-1(N)-arylsulfonylimidazolidinones have been found to be the potential anticancer agent.

Subjects :: Biochemistry
medicine.drug_class
Chemistry
In vitro cytotoxicity
medicine
Cytotoxic T cell
General Medicine
Human cell
Pharmacophore
Sulfonylurea

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