The Analysis of Osteoconducting Ability of Alpha-Tricalcium Phosphate-Based Bone Filler Powder

Titanium alloy(Ti-6Al-4V, Samsung techwin, Korea) rods with diameter of 2.5mm were used as the implant materials. Polymethyl methacrylate(PMMA) bone cements(CMW, USA) were used as bone cement and -tricalcium phosphate(TCP)-based bone filler powder was used as osteoconductive additives. Hydroxyapatite(HA) was the desired end product after hydrolysis of the -TCP-based bone filler powder mixed with the blood. In animal study using rabbits, we divided the group into A, B, C and D. Rabbits were sacrificed at 1, 3, 9 weeks after implantation and the affinity index and bone density were calculated. X-ray diffraction patterns of HA formed by hydrolysis of -TCP-based bone filler powder showed higher and higher intensity in HA peak with increase of time period. There was more bone density increase in the group B and D containing - TCP-based bone filler powder around implant site than in the group A and C(p