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Global changes: Bacterial populations, environmental pressures and the future of predicting antimicrobial resistance and pathogenicity
- Source :
- Microbiology Australia. 30:76
- Publication Year :
- 2009
- Publisher :
- CSIRO Publishing, 2009.
-
Abstract
- Robert Koch quickly recognised that there was no universal environmental condition which would support the growth of all bacteria. Bacterial cells within clonal populations can show phenotypic variation due to internal stochastic processes. Variation between individual cells can be beneficial as well as detrimental to the survival of a population exposed to stress such as change in environmental conditions and many other variables such as selective antibiotic pressure. Variation in the level of proteins relevant for growth or survival among individual cells in a population is likely to play a role in drug resistance and disease. Cells reproduce by incorporating metabolite molecules and die at rates dependent on their gene expression and environmental states.
- Subjects :
- Microbiology (medical)
Genetics
education.field_of_study
medicine.drug_class
Ecology
Population
Antibiotics
Public Health, Environmental and Occupational Health
Drug resistance
Disease
Biology
Pathogenicity
biology.organism_classification
Applied Microbiology and Biotechnology
Microbiology
Phenotype
Antibiotic resistance
medicine
education
Bacteria
Subjects
Details
- ISSN :
- 13244272
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Microbiology Australia
- Accession number :
- edsair.doi...........577570ac1034659dbd7e3ecc86f97235