PHYSER: An Algorithm to Detect Sequencing Errors from Phylogenetic Information

Authors :: Jorge Alvarez-Jarreta
Elvira Mayordomo
Eduardo Ruiz-Pesini
Source :: Advances in Intelligent and Soft Computing ISBN: 9783642288388, PACBB
Publication Year :: 2012
Publisher :: Springer Berlin Heidelberg, 2012.
Abstract: Sequencing errors can be difficult to detect due to the high rate of production of new data, which makes manual curation unfeasible. To address these shortcomings we have developed a phylogenetic inspired algorithm to assess the quality of new sequences given a related phylogeny. Its performance and efficiency have been evaluated with human mitochondrial DNA data.

Subjects :: High rate
Phylogenetic tree
Phylogenetics
Computer science
Algorithm
Manual curation
Human mitochondrial genetics

ISBN :: 978-3-642-28838-8
ISBNs :: 9783642288388
Database :: OpenAIRE
Journal :: Advances in Intelligent and Soft Computing ISBN: 9783642288388, PACBB
Accession number :: edsair.doi...........5755f51b6589beb7fbef5dff7dbcd44a
Full Text :: https://doi.org/10.1007/978-3-642-28839-5_12