The combination of GDC-0980, a PI3K/mTOR kinase inhibitor and BAY-86-9766, a MEK inhibitor is able to induce cell growth inhibition of HER2 positive Trastuzumab resistant gastric cancer cell lines

Authors :: Fortunato Ciardiello
Anna Capasso
Maria Maddalena Laterza
F. De Vita
Angelica Petrillo
Valentina Belli
B. Savastano
F. Morgillo
Michele Orditura
Jole Ventriglia
Giuseppe Tirino
Luca Pompella
E. Martinelli
Source :: Annals of Oncology. 27:iv21
Publication Year :: 2016
Publisher :: Elsevier BV, 2016.

Subjects :: Oncology
Cell growth
Trastuzumab
Kinase
business.industry
MEK inhibitor
Cancer research
medicine
Hematology
business
PI3K/AKT/mTOR pathway
Gastric cancer cell
medicine.drug

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