Synthesis of Multisubstituted Dihydroquinoxaline Derivatives by TandemN-Alkylation and Addition Reactions of 3-Oxoquinoxaline-2-carboxylates

This report describes a one-pot synthesis of multisubstituted dihydroquinoxalin-2-ones using an umpolung N-alkylation followed by oxidation and C-alkylation reactions. Moreover, the synthesis of tricyclic compounds containing a dihydroquinoxaline skeleton was carried out by ring closing metathesis (RCM) of the resulting N,C-bis-addition products containing olefins.