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Orthogonal Functions for Evaluating Social Distancing Impact on CoVID-19 Spread

Authors :
Genghmun Eng
Publication Year :
2020
Publisher :
Cold Spring Harbor Laboratory, 2020.

Abstract

Early CoVID-19 growth often obeys: , with Ko = [(ln 2)/(tdbl)], where tdbl is the pandemic doubling time, prior to society-wide Social Distancing. Previously, we modeled Social Distancing with tdbl as a linear function of time, where N [t] 1 ≈ exp[+KAt/ (1+,γot)] is used here. Additional parameters besides {Ko, γo} are needed to better model different ρ[t] = dN [t]/dt shapes. Thus, a new Orthogonal Function Model [OFM] is developed here using these orthogonal function series: where N (Z) and Z[t] form an implicit N [t] N (Z[t]) function, giving: with Lm(Z) being the Laguerre Polynomials. At large MF values, nearly arbitrary functions for N [t] and ρ [t] = dN [t]/dt can be accommodated. How to determine {KA, γo} and the {gm; m = (0, +MF)} constants from any given N (Z) dataset is derived, with ρ [t] set by: The bing com USA CoVID-19 data was analyzed using MF = (0, 1, 2) in the OFM. All results agreed to within about 10 percent, showing model robustness. Averaging over all these predictions gives the following overall estimates for the number of USA CoVID-19 cases at the pandemic end: which compares the pre- and post-early May bing com revisions. The CoVID-19 pandemic in Italy was examined next. The MF = 2 limit was inadequate to model the Italy ρ [t] pandemic tail. Thus, regions with a quick CoVID-19 pandemic shutoff may have additional Social Distancing factors operating, beyond what can be easily modeled by just progressively lengthening pandemic doubling times (with 13 Figures).

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........5680dd0704d760baf6e4c74c4409417d