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Graphene coated fiber optic surface plasmon resonance biosensor for the DNA hybridization detection: Simulation analysis
- Source :
- Optics Communications. 383:186-190
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- In this paper, a graphene coated optical fiber surface plasmon resonance (SPR) biosensor is presented for the detection of DNA Hybridization. For the proposed sensor, a four layer model (fiber core /metal /sensing layer /sample) where a sheet of graphene (biomolecular recognition elements ( BRE)) acting as a sensing layer is coated around the gold film because graphene enhances the sensitivity of fiber optic SPR biosensor. Numerical analysis shows the variation of resonance wavelength and spectrum of transmitted power for mismatched DNA strands and for complementary DNA strands. For mismatched DNA strands variation is negligible whereas for complementary DNA strands is considerably countable. Proposed sensor successfully distinguishes hybridization and single nucleotide polymorphisms (SNP) by observing the variation level of resonance wavelength and spectrum of transmitted power.
- Subjects :
- Optical fiber
Materials science
Graphene
Nanotechnology
02 engineering and technology
021001 nanoscience & nanotechnology
01 natural sciences
Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
law.invention
010309 optics
Core (optical fiber)
chemistry.chemical_compound
chemistry
law
0103 physical sciences
Fiber
Electrical and Electronic Engineering
Physical and Theoretical Chemistry
Surface plasmon resonance
0210 nano-technology
Layer (electronics)
Biosensor
DNA
Subjects
Details
- ISSN :
- 00304018
- Volume :
- 383
- Database :
- OpenAIRE
- Journal :
- Optics Communications
- Accession number :
- edsair.doi...........566524f7d934ac35535879f16126e4bb