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A Study to Assess Prevalence and Drug Utilization Pattern in Hepatic Impairment Patients with or without Comorbidities in a Tertiary Care Teaching Hospital
- Source :
- Journal of Young Pharmacists. 13:167-171
- Publication Year :
- 2021
- Publisher :
- EManuscript Technologies, 2021.
-
Abstract
- Background: The liver is the core of metabolic activity in the body. Around 50% of the classes of drugs are known to be hepatotoxic. Thus prescribing medications in patients with liver disease is indeed a challenging task. Objectives: To study the prevalence and to carry out the drug utilization evaluation of the therapy prescribed among hepatic impairment patients. Methodology: A prospective observational study was carried out for six months among inpatients of the medicine department of Chigateri district hospital. Patients were enrolled on the basis of inclusion criteria; data was collected using a data collection form and results were analyzed using MS Excel. Results: A total of 160 patients were enrolled, the most prevalent condition was alcoholic liver disease (n=66, 41.25%) followed by chronic liver disease (n=47, 29.38%) and hepatic encephalopathy (n=12, 7.5%). Out of 1466 drugs been prescribed, 795 drugs were used specifically for hepatic impairment. Drugs used to treat oedema (diuretics) were most commonly prescribed (n=198, 25%) followed by gall stone dissolution agents (n=124, 16%) and sugars (n=97, 12%). Conclusion: Alcoholic liver disease was the most prevalent hepatic condition, followed by chronic liver disease. The diuretics were the most widely used hepato-specific drugs among the patients. Key words: Drug utilization pattern, Hepatic impairment, Abstinence, Diuretics.
- Subjects :
- Drug Utilization
Alcoholic liver disease
medicine.medical_specialty
business.industry
Hepatic impairment
media_common.quotation_subject
Abstinence
medicine.disease
Chronic liver disease
Liver disease
Internal medicine
medicine
Observational study
General Pharmacology, Toxicology and Pharmaceutics
business
Hepatic encephalopathy
media_common
Subjects
Details
- ISSN :
- 09751505 and 09751483
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Journal of Young Pharmacists
- Accession number :
- edsair.doi...........55d60ac5585c66d889eef062f23c52b5