Back to Search
Start Over
Stereoselective synthesis of alcohols. Part LV. Domino hydroformylation-allylboration-hydroformylation reactions to give trans-perhydropyrano[3,2-b]pyridine derivatives
- Source :
- New Journal of Chemistry. 25:369-373
- Publication Year :
- 2001
- Publisher :
- Royal Society of Chemistry (RSC), 2001.
-
Abstract
- N-Allyl-(E)-γ-aminoallyl boronates 8 and 18, when subjected to hydroformylation conditions, enter into a domino hydroformylation-allylboration-hydroformylation reaction cascade to generate the bicyclic N,O-heterocycles 12 and 20. On reaction of the methallyl compound 8b a stereogenic center is generated in the initial hydroformylation, which controls the relative configuration of the two new stereogenic centers resulting from the allylboration reaction.
Details
- ISSN :
- 13699261 and 11440546
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- New Journal of Chemistry
- Accession number :
- edsair.doi...........5509145023001faa500560647c5bc351