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Device therapy for atrial septal defects in a multicenter cohort: Acute outcomes and adverse events
- Source :
- Catheterization and Cardiovascular Interventions. 85:227-233
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Background: Secundum atrial septal defect (ASD) closure devices were granted approval based on industry-sponsored, prospective, nonrandomized, single device studies, demonstrating acceptable efficacy and safety in selected patients. We sought to report community practice and outcomes. Methods and Results: Procedure specific data was collected on cases considered for ASD closure in the congenital cardiac catheterization project on outcomes (C3PO) between February 1, 2007 and June 31, 2010. Eight centers contributed data during this time period. All adverse events (AE) were independently reviewed and classified by a five level severity scale. In 40 months (2/07–6/10), 653 of 688 ASDs were occluded with a single device using an AMPLATZER® Septal Occluder (ASO) in 566 (87%), GORE® HELEX® Septal Occluder (HSO) in 33 (5%), and a CardioSEAL® or STARFlex™ device (CSD) in 54 (8%). Most patients had an isolated ASD (93%). 85% were >2 years of age. The ASD median diameter was 12 mm [8,16] for ASO, with smaller diameters in HSO 8 mm [7,10] and CSD 8 mm [5,10] (P
- Subjects :
- medicine.medical_specialty
business.industry
medicine.medical_treatment
Septum secundum
General Medicine
Atrial septal defects
Surgery
Device therapy
Cohort
medicine
Radiology, Nuclear Medicine and imaging
Septal Occluder
Cardiology and Cardiovascular Medicine
High severity
Adverse effect
business
Cardiac catheterization
Subjects
Details
- ISSN :
- 15221946
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- Catheterization and Cardiovascular Interventions
- Accession number :
- edsair.doi...........54f26ee31cb488c213cb0e44e1dd3deb