How Safe is Progesterone? Acute Pulmonary Embolisms (APE) Alleged to Progesterone

During the interval period, she almost collapsed from heavy vaginal bleeding and therefore admitted and investigated. Complete blood count showed features of pancytopenia (low hemoglobin estimation reported as 5 gm%, low WBC, RBC and also platelets). For this she was transfused with 3 units of packed cell. In oral hormone therapy, medroxy progesterone acetate was substituted by norethisterone acetate and as usual, was sent home with a decision to operate later once there was subsidence of body edema and return in the tissue perfusion. This was also because on the unavailability of attending doctor.