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The synthesis and antibacterial activity study of ruthenium-based metallodrugs with a membrane-disruptive mechanism against Staphylococcus aureus
- Source :
- Dalton Transactions. 51:14980-14992
- Publication Year :
- 2022
- Publisher :
- Royal Society of Chemistry (RSC), 2022.
-
Abstract
- Ruthenium-based antibacterial agents with a membrane-disruptive mechanism were designed and synthesized. The complex Ru2 showed excellent antibacterial activity against S. aureus in vitro and in vivo.
- Subjects :
- Inorganic Chemistry
Subjects
Details
- ISSN :
- 14779234 and 14779226
- Volume :
- 51
- Database :
- OpenAIRE
- Journal :
- Dalton Transactions
- Accession number :
- edsair.doi...........542d27e8fb85929b031db1be8c0117a7
- Full Text :
- https://doi.org/10.1039/d2dt01531e