ChemInform Abstract: Isolation and Characterization of the Major Equilibrium Product of FK- 520

Authors :: Robert A. Reamer
John M. Ballard
Dennis Kuczynski
Francis P. Gailliot
G. J. Mcmanemin
Theresa K. Natishan
Barry C. Buckland
Richard S. Egan
Source :: ChemInform. 26
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: The existence of an isomeric form in equilibrium with the major component of FK-520 in polar solutions has been demonstrated. This minor component has been isolated in high yield and purity by a novel crystallization strategy and preparative HPLC. The equilibrium product was characterized by NMR and MS.

Subjects :: Preparative hplc
Chemistry
Computational chemistry
law
Component (thermodynamics)
Product (mathematics)
Yield (chemistry)
Polar
General Medicine
Crystallization
law.invention
Characterization (materials science)

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