Zelluläre Logistik der Mitochondrienvererbung

Partitioning and inheritance of mitochondria upon cell division depends on cytoskeleton-dependent transport and organelle anchoring sites at the cell cortex. In asymmetrically dividing cells the mitochondria of both daughter cells may differ in their properties. In yeast cells intact mitochondria are transported towards the bud whereas old and damaged organelles are retained in the mother cell. Similarly, in stem cell division young mitochondria are selected to maintain stem cell properties.