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Prevalence of adenomas and sessile serrated adenomas in Chinese compared with Caucasians
Prevalence of adenomas and sessile serrated adenomas in Chinese compared with Caucasians
- Source :
- Journal of Gastroenterology and Hepatology. 28:608-612
- Publication Year :
- 2013
- Publisher :
- Wiley, 2013.
-
Abstract
- Background and Aims Colonic adenomas and sessile serrated adenomas (SSA) are the most common premalignant polyps identified at colonoscopy. This study compares the prevalence of neoplastic polyps in Chinese and Caucasians in a general gastroenterology outpatient practice in Australia. Methods This study included consecutive unselected colonoscopies performed for standard clinical indications by a single endoscopist (JMH). All polyps detected were measured, resected, and sent for histopathology. The prevalence of adenomas, advanced adenomas, SSA, and cancer in the Chinese and Caucasian cohorts were compared. Advanced adenomas were defined as adenomas > 10 mm, villous histology, or high-grade dysplasia. Results The study included 346 Chinese and 654 Caucasians. There was no significant difference in the baseline characteristics including age, gender, and indications of colonoscopy, although Chinese were more likely to present with rectal bleeding (22.8% vs 15.9%, P = 0.01). The prevalence of adenomatous polyps was similar in both Caucasians (34.3%) and Chinese (35.3%). However, advanced adenomas were more significantly common in Caucasians (11.3%) compared with Chinese (4.6%) (P
- Subjects :
- medicine.medical_specialty
Hepatology
medicine.diagnostic_test
Adenoma
business.industry
Gastroenterology
Colonoscopy
Retrospective cohort study
Odds ratio
medicine.disease
digestive system diseases
Confidence interval
stomatognathic diseases
Dysplasia
Internal medicine
medicine
business
Cohort study
Sessile serrated adenoma
Subjects
Details
- ISSN :
- 08159319
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Journal of Gastroenterology and Hepatology
- Accession number :
- edsair.doi...........539cb865b6488de6259cdc4bcb53eb57
- Full Text :
- https://doi.org/10.1111/jgh.12100