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Prevalence of adenomas and sessile serrated adenomas in Chinese compared with Caucasians

Prevalence of adenomas and sessile serrated adenomas in Chinese compared with Caucasians

Authors :
Jason Behary
Vivek Kumbhari
Jason M. Hui
Source :
Journal of Gastroenterology and Hepatology. 28:608-612
Publication Year :
2013
Publisher :
Wiley, 2013.

Abstract

Background and Aims Colonic adenomas and sessile serrated adenomas (SSA) are the most common premalignant polyps identified at colonoscopy. This study compares the prevalence of neoplastic polyps in Chinese and Caucasians in a general gastroenterology outpatient practice in Australia. Methods This study included consecutive unselected colonoscopies performed for standard clinical indications by a single endoscopist (JMH). All polyps detected were measured, resected, and sent for histopathology. The prevalence of adenomas, advanced adenomas, SSA, and cancer in the Chinese and Caucasian cohorts were compared. Advanced adenomas were defined as adenomas > 10 mm, villous histology, or high-grade dysplasia. Results The study included 346 Chinese and 654 Caucasians. There was no significant difference in the baseline characteristics including age, gender, and indications of colonoscopy, although Chinese were more likely to present with rectal bleeding (22.8% vs 15.9%, P = 0.01). The prevalence of adenomatous polyps was similar in both Caucasians (34.3%) and Chinese (35.3%). However, advanced adenomas were more significantly common in Caucasians (11.3%) compared with Chinese (4.6%) (P

Details

ISSN :
08159319
Volume :
28
Database :
OpenAIRE
Journal :
Journal of Gastroenterology and Hepatology
Accession number :
edsair.doi...........539cb865b6488de6259cdc4bcb53eb57
Full Text :
https://doi.org/10.1111/jgh.12100