Endometrial Carcinoma with Pleural Metastasis

Background There have been a limited number of studies giving the incidence of plearal metastasis from female genital tract tumors. Case An unusual case occurred of recurrent pleural malignant effusion associated with disseminated serous papillary endometrial adenocarcinoma (EC). A total abdominal hysterectomy with bilateral salpingo-oophorectomy, pelvic lymphademectomy, appendectomy and omentectomy was performed. Trentment of the pleural malignant effasion consisted of thoracotomy with partial decortication, systemic chemotherapy and radiotherapy. The patient died of circulatory failure 8 months after the primary diagnosis Conclusion Although the plcura is a race site of widespread EC, one should recognize the possibility of pleural spread from female genital tract neoplasms presenting with associated symptoms. Cytopathologic examination of the pleural effusion and the finding of arrcinoma cells mandate an investigation for the primary site of the neophasm by a multidisciplinary group.