A Comparison of the Collodion-Particle Technic with Other Methods of Measuring Antibody

Summary The collodion-particle technic described by Cannon and Marshall was compared with the gelatin-interface test and the complement-fixation test. The comparisons were made using rabbit antisera for ovalbumin, ragweed-pollen extract and horse-serum. The collodion-particle technic consistently permitted the greatest dilution of serum without loss of the ability to give an easily visible antigen-antibody reaction. The titers obtained with the collodion-particle technic paralleled those obtained with the gelatin-interface and the complement-fixation tests.