Mutation burden and microsatellite instability in colorectal cancer in Japan and US

Authors :: Shujiro Okuda
Stephen Lyle
Julie Y. Tse
Takuya Ando
Alexei Protopopov
Takashi Kobayashi
Kazuki Moro
Kazuaki Takabe
Daiki Soma
Yoshifumi Shimada
Yusuke Muneoka
Hiroshi Izutsu
Junko Tsuchida
Toshifumi Wakai
Kizuki Yuza
Hitoshi Kameyama
Masayuki Nagahashi
Masato Nakajima
Kohei Akazawa
Hiroshi Ichikawa
Source :: Journal of Clinical Oncology. 34:e15103-e15103
Publication Year :: 2016
Publisher :: American Society of Clinical Oncology (ASCO), 2016.
Abstract: e15103Background: It has been previously documented that high somatic mutational rates in cancer as determined by whole genome sequencing correlates with high microsatellite instability (MSI-H) and...

Subjects :: Whole genome sequencing
Genetics
Cancer Research
Somatic cell
Colorectal cancer
Cancer
Microsatellite instability
Biology
medicine.disease
digestive system diseases
03 medical and health sciences
0302 clinical medicine
Oncology
030220 oncology & carcinogenesis
Mutation (genetic algorithm)
medicine
030211 gastroenterology & hepatology

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