Evaluation of antimycobacterial, antioxidant, and anticancer activities of CuO nanoparticles through cobalt doping

Here, we report the synthesis of cobalt-doped copper oxide nanoparticles (CuO–NPs) via combustion strategy with lime juice as a reductant at relatively low temperature of 600 °C and at shorter duration of 3 h. Powder X-ray diffraction (XRD) results revealed that, every compound was in monoclinic structure with space group C12/C1 (No. 15) and average particle size were found to be 18–21 nm. These NPs were used to evaluate the antimycobacterial activity against “Mycobacterium tuberculosis H37Rv ATCC 27294”, “Mycobacterium abscessus ATCC 19977”, “Mycobacterium fortuitum ATCC 6841”, “Mycobacterium chelonae ATCC 35752” and anticancer activity on MDA-MB-231. Antioxidant activity was evaluated by DPPH method. The results showed that, doping CuO with cobalt improved the antimycobacterial, anticancer and scavenging activities of CuO–NPs.