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Reaction of 5,5-dialkyl-2-halo-6-hydroxy-5,6-dihydro-1H-pyridine-3,4,4-tricarbonitriles with Morpholine
- Source :
- Russian Journal of Organic Chemistry. 45:1541-1545
- Publication Year :
- 2009
- Publisher :
- Pleiades Publishing Ltd, 2009.
-
Abstract
- 5,5-Dialkyl-2-halo-6-hydroxy-5,6-dihydro-1H-pyridine-3,4,4-tricarbonitriles reacted with morpholine in aprotic solvent to give the corresponding 3,3-dialkyl-4,5-dicyano-6-halo-2-morpholino-1,2,3,4-tetrahydropyridine-4-carboxamides, while analogous reaction in amphiprotic solvent resulted in the formation of 8,8-dialkyl-3-halo-6-oxo-2,7-diazabicyclo[3.2.1]oct-3-ene-4,5-dicarbonitriles.
Details
- ISSN :
- 16083393 and 10704280
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- Russian Journal of Organic Chemistry
- Accession number :
- edsair.doi...........52a6aa80978eed24172a47fc9a12cd23
- Full Text :
- https://doi.org/10.1134/s1070428009100212