Calcium Excretion and Hypercalciuria

Calcium is the principal constituent of most kidney stones, which seems to originate as a crystalline precipitate in a supersaturated medium. Calcium concentration in the urine therefore plays an important part in the genesis of calcium stone disease and is of course determined by the relation between the rate of calcium excretion and the rate of urine flow. The present paper will be primarily concerned with examining calcium excretion rate and the factors which determine this rate in health and disease.