A Dielectric Modulated MOS transistor for Biosensing

The study on biosensors is recent ubiquitous research in biomedical diagnosis and employed in wide range of applications as detection of disease-causing biomolecules, point-of-care monitoring of treatment, marker indicator testing, environmental monitoring, drug discovery, forensics and biomedical research etc. The biosensor devices convert biomolecule recognized events to detectable signals. A wide range of techniques can be used for the development of biosensors. This paper initially provides the investigation for biosensing of biomolecules by analyzing and summarizing remarkable studies on heterostructure MOS devices which can capture biomolecules in the designated device regions. A dual-gate MOS device having cavity regions which can trap the biomolecules has been proposed and simulated to study electrical characteristics and threshold variation. The device can sense and detect the presence of biomolecules of dimensions up to 500nmx60nm. The proposed device can be further calibrated for several device and design parameters. Accordingly, the simulated results would be analyzed to report trade-off and other significant features to develop noble heterostructure MOS devices for biosensing.