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A Case of Thyrotoxic Periodic Paralysis with Rhabdomyolysis
- Source :
- Journal of Korean Endocrine Society. 23:425
- Publication Year :
- 2008
- Publisher :
- Korean Endocrine Society, 2008.
-
Abstract
- Hyperthyroidism combined with rhabdomyolysis is extremely rare. There are only 6 reported cases of hyperthyroidism accompanied with rhabdomyolysis in the medical literature. Rhabdomyolysis is a syndrome involving the breakdown of skeletal muscle, and this causes myoglobin and intracellular protein to leak into the circulation. The causes of rhabdomyolysis include trauma, electrolyte abnormality, infection, drug, toxin and hypothyroidism. We report here on a patient who presented with thyrotoxic periodic paralysis and rhabdomyolysis with hypokalemia. He complained of lower leg paralysis along with muscle tenderness, and the laboratory findings showed elevated creatine kinase (CK) levels. After treatment by hydration, potassium replacement and drug medication, including propylthiouracil and beta-blocker, his CK levels were normalized and his symptoms were much improved. For patient with thyrotoxic periodic paralysis and muscle tenderness, the possibility of rhabdomyolysis should be clarified by examining the CK levels. (J Korean Endocr Soc
- Subjects :
- medicine.medical_specialty
endocrine system diseases
biology
business.industry
Skeletal muscle
Thyrotoxic periodic paralysis
Periodic paralysis
medicine.disease
Hypokalemia
Endocrinology
medicine.anatomical_structure
Internal medicine
Anesthesia
medicine
biology.protein
Creatine kinase
Propylthiouracil
medicine.symptom
Muscle tenderness
business
Rhabdomyolysis
medicine.drug
Subjects
Details
- ISSN :
- 10156380
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of Korean Endocrine Society
- Accession number :
- edsair.doi...........50a3c86d62de7c8277fb001af39c5fe9