Patterns of AKT, mTOR, ERK, and STAT3 pathway activation in MGUS, smoldering multiple myeloma, and multiple myeloma

Authors :: Shaji Kumar
Teresa K. Kimlinger
Jeremy T. Larsen
S. Vincent Rajkumar
Vijay Ramakrishnan
Linda Wellik
Source :: Journal of Clinical Oncology. 33:8589-8589
Publication Year :: 2015
Publisher :: American Society of Clinical Oncology (ASCO), 2015.
Abstract: 8589 Background: Constitutive activation of key signaling pathways supports proliferation in multiple myeloma (MM). However, pathway activation in MGUS and smoldering multiple myeloma (SMM) compare...

Subjects :: MAPK/ERK pathway
Cancer Research
biology
business.industry
medicine.disease
Oncology
immune system diseases
hemic and lymphatic diseases
Immunology
Cancer research
biology.protein
Medicine
Signal transduction
business
STAT3
Protein kinase B
PI3K/AKT/mTOR pathway
Multiple myeloma

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