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AMER1 Is a Frequently Mutated Gene in Colorectal Cancer—Letter

Authors :
Gemma Aiza
Rebeca Sanz-Pamplona
Victor Moreno
Gabriel Capellá
Laura Valle
Sara González
Matilde Navarro
Pilar Mur
Source :
Clinical Cancer Research. 21:4985-4985
Publication Year :
2015
Publisher :
American Association for Cancer Research (AACR), 2015.

Abstract

In the article by Sanz-Pamplona and colleagues ([1][1]), functionally relevant mutations in AMER1 were identified in approximately 10% of stage II colorectal tumors, reinforcing its role as a driver gene in colorectal cancer, as occurs with APC , KRAS , or TP53 . AMER1 codifies a membrane protein

Details

ISSN :
15573265 and 10780432
Volume :
21
Database :
OpenAIRE
Journal :
Clinical Cancer Research
Accession number :
edsair.doi...........4f06461f252710f6559c867e6a473941