ChemInform Abstract: From Cycloolefins to Linear C2-Symmetrical 1,4-Diamino-2,3-diol Building Blocks-Peptide Mimetics, Biocatalysis, and Pinacol Coupling of α-Amino Aldehydes

Technical olefins and azodicarbonic ester are the starting materials for C2 -symmetrical C16 and C12 1,4-diamino-2,3-diol building blocks (see structure), which are of interest for a variable access to potentially bioactive compounds (peptide mimetics, enzyme inhibitors). MOM = methoxymethyl.