Serum albumin concentration predicts the prognosis of patients with acute decompensated heart failure

Purpose: Malnutrition is common in patients with heart failure. We evaluated the influence of serum albumin concentration on the prognosis of the patients with Acute Decompensated Heart Failure (ADHF). Methods: 728 patients with ADHF were divided into 4 groups by the quartile of serum albumin concentration on admission (Q1: 1.8–3.1g/dl; Q2: 3.2–3.5g/dl; Q3: 3.6–3.8g/dl; Q4: 3.9–4.9g/dl). The short-term and long-term prognoses of 4 groups were investigated retrospectively. Results: In-hospital mortality of Q1, Q2, Q3, and Q4 group were 13.8%, 6.2%, 3.4%, and 3.0%, respectively. During the mean follow-up periods of 569±631 days, 180 patients (24.7%) died for all cause and 105 patients (14.4%) died for cardiac cause. As compared with the highest albumin group (Q4 group), the hazard ratio for all-cause death of the lowest albumin group (Q1 group) was 3.46 (95% CI; 2.24–5.40) in the unadjusted model, and 2.77 (95% CI; 1.79–4.33) in the age- and sex- adjusted model. ![Figure][1] Albumin concentration and prognoses Conclusion: Serum albumin concentration is useful to predict the prognosis of patients with ADHF. [1]: pending:yes