Abnormal Platelet Aggregation in Patients with Bartter’s Syndrome

Bartter’s syndrome is characterized by hypokalemia, hyperreninemia, hyperaldosteronism without hypertension, and juxtaglomerular cell hyperplasia.1 Recent studies have demonstrated an increase of the urinary excretion of prostaglandins (PGs) PGE2, PGF2α 2–4 and 6-keto PGF1α 5,6 in cases of Bartter’s syndrome.