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Preparation and characterization of carnauba wax nanostructured lipid carriers containing benzophenone-3
- Source :
- International Journal of Cosmetic Science. 33:312-321
- Publication Year :
- 2011
- Publisher :
- Wiley, 2011.
-
Abstract
- Nanostructured lipid carriers (NLCs) are potential active delivery systems based on mixtures of solid lipids and liquid oil. In this paper, aqueous dispersions of NLCs were prepared by a hot high-pressure homogenization technique using carnauba wax as the solid lipid and isodecyl oleate as the liquid oil. The preparation and stability parameters of benzophenone-3-loaded NLCs have been investigated concerning particle size, zeta potential and loading capacity to encapsulate benzophenone-3, a molecular sunscreen. The current investigation illustrates the effect of the composition of the lipid mixture on the entrapment efficiency, in vitro release and stability of benzophenone-3-loaded in these NLCs. A loading capacity of approximately 5% of benzophenone-3 (m(BZ-3) /m(lipids) ) was characteristic of these systems.
- Subjects :
- Aging
Chromatography
Pharmaceutical Science
Aqueous dispersion
02 engineering and technology
Dermatology
Calorimetry
021001 nanoscience & nanotechnology
030226 pharmacology & pharmacy
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Colloid and Surface Chemistry
chemistry
Chemistry (miscellaneous)
Drug Discovery
Zeta potential
Benzophenone
Particle size
Oxybenzone
Carnauba wax
0210 nano-technology
Drug carrier
Subjects
Details
- ISSN :
- 01425463
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- International Journal of Cosmetic Science
- Accession number :
- edsair.doi...........4af3b807f626785ca348db3180e1c0e4