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Clinical Results After Application of Bevacizumab in Recurrent Pterygium
- Source :
- Journal of the Korean Ophthalmological Society. 49:1901
- Publication Year :
- 2008
- Publisher :
- Korean Ophthalmological Society, 2008.
-
Abstract
- Purpose: To clinically establish the effectiveness and safety of bevacizumab on recurrent pterygium. Methods: Twenty patients with recurrent pterygium were given a subconjunctival injection of 0.3 cc bevacizumab, and were evaluated for periodic clinical results at 1 week, 2 weeks, 4 weeks, and every month thereafter. The patients were also evaluated for clinical results and complications. Results: Of recurrent pterygium patients with bevacizumab injection, the conjunctival injection decreased maximally after 1 to 2 weeks, but significantly increased at 4 weeks (above the lowest level measured at 1 to 2 weeks), and no patient presented conjunctival injection above the pre-injection level at 3 months, except in 2 cases. Two weeks after the injection, ICG anterior segment angiography revealed a significant decrease (30.14+17.69%) in vessel thickness of the pterygium 2 weeks after the bevacizumab injection compared to before the injection. There had been no cases of progression of pterygium, and no ocular or systemic complications due to bevacizumab. Conclusions: As shown above in the results, subconjunctival injection of 0.3 cc bevacizumab decreased the conjunctival injection and effectively suppressed any further progression of pterygium. Thus, bevacizumab subconjunctival injection appears to be effective in recurrent pterygium treatment instead of surgical methods.
- Subjects :
- medicine.medical_specialty
Bevacizumab Injection
Conjunctival injection
genetic structures
Bevacizumab
medicine.diagnostic_test
business.industry
medicine.disease
eye diseases
Surgery
Surgical methods
Pterygium
Ophthalmology
Angiography
medicine
Recurrent pterygium
sense organs
Subconjunctival injection
business
medicine.drug
Subjects
Details
- ISSN :
- 03786471
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Journal of the Korean Ophthalmological Society
- Accession number :
- edsair.doi...........4aa3e03c670e59777563a11cc4e8ceb3