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Synthesis and crystal structure of methyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-(pyrimidin-2-ylamino)acrylate

Authors :
Jing Zheng
Chun-Yang Zheng
Dun-Jia Wang
Lian-Ying Lu
Source :
Research on Chemical Intermediates. 38:2355-2363
Publication Year :
2012
Publisher :
Springer Science and Business Media LLC, 2012.

Abstract

Methyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-(pyrimidin-2-ylamino)acrylate has been prepared. Its crystal structure is discussed. The compound crystallizes in the triclinic space group P-1 with a = 11.6259 (7) A, b = 11.8789 (7) A, c = 13.9206 (5) A, α = 68.0250 (10)°, β = 77.5660 (10)°, γ = 62.4950 (10)°, V = 1579.18 (14) A3, Z = 4. There are two independent but chemically identical molecules in the asymmetric unit. The molecules are packed in the crystal structure by weak intermolecular C–H···O and C–H···F interactions.

Details

ISSN :
15685675 and 09226168
Volume :
38
Database :
OpenAIRE
Journal :
Research on Chemical Intermediates
Accession number :
edsair.doi...........4a467aefa7fe3691e50ed1a46ed2bec9
Full Text :
https://doi.org/10.1007/s11164-012-0551-8