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Copper-Catalyzed Hydrogen/Iodine Exchange in Terminal and 1-Iodoalkynes
- Source :
- ACS Catalysis. 7:2505-2510
- Publication Year :
- 2017
- Publisher :
- American Chemical Society (ACS), 2017.
-
Abstract
- Detailed kinetic profiles of the copper-catalyzed exchange between the acetylenic proton and iodide of terminal and 1-iodophenylacetylenes are reported. The electronic nature of the alkynes does not influence the equilibrium of the exchange (Keq = 1), only the rate of equilibration. Notably, the profiles are the same for electron-rich, methyl-substituted phenylacetylenes but are divergent for electron-deficient, trifluoromethyl-substituted variants. The heretofore unreported exchange process yields practical considerations regarding reactions involving iodo and terminal alkynes.
- Subjects :
- chemistry.chemical_classification
Hydrogen
Proton
010405 organic chemistry
Chemistry
Iodide
chemistry.chemical_element
General Chemistry
010402 general chemistry
Photochemistry
Iodine
01 natural sciences
Catalysis
0104 chemical sciences
3. Good health
Terminal (electronics)
Computational chemistry
Copper catalyzed
Subjects
Details
- ISSN :
- 21555435
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- ACS Catalysis
- Accession number :
- edsair.doi...........4994aa5f6f411a56a1a56a35ff0ae5ac