Ultrastructural Study of Peripheral Nerve in Guillain-Barré Syndrome Presence of Mononuclear Cells in Axons

As has been shown during the course of experimental allergic neuritis, in the Guillain-Barre syndrome there is an invasion of the myelin sheath in certain fibres by a mononuclear cell, with an intact axon. In a series of 45 cases we have been able to show this feature in 31 cases. In certain cases the cytoplasm prolongation of the invading cell was seen in the myelin sheath, forcing apart two neighbouring layers.