Synthesis and Copper Coordination Chemistry of Hindered 1,4,7-Triazacyclononane Ligands with Amide Appendages

Copper complexes of the new ligands1a LPiv and LRAmR‘ that comprise 1,4-diisopropyl-1,4,7-triazacyclononanes linked to secondary and tertiary amide groups were prepared and characterized, with a particular view toward evaluating amide structural, spectroscopic, and potential hydrogen-bonding influences of relevance to ongoing copper−dioxygen reactivity studies. X-ray crystal structures of the Cu(I) complexes [LCu(CH3CN)]X (L = LHAmMe, X = ClO4; L = LPiv, X = CF3SO3) revealed typical 4-coordinate geometries with the amide dangling free, while those of the Cu(II) compounds [LCuCl]X (L = LHAmMe, X = ClO4; L = LMeAmH, X = PF6) and [LPivCu(O3SCF3)]O3SCF3 showed 5-coordinate square pyramidal geometries with the amide coordinated to the metal via its carbonyl oxygen atom. Analysis of FTIR spectra of the aforementioned compounds and the carbon monoxide adducts [LMeAmR‘Cu(CO)]SbF6 (R‘ = H or Me) allowed (i) identification of signatures of amide structural features, hydrogen bonding, and metal coordination and (ii)...