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Detection and Characterization of Two Phenotypes of Candida parapsilosis in South Korea: Clinical Features and Microbiological Findings

Authors :
Jung-Hyun Byun
Eun Jeong Won
Hae Weon Cho
Daewon Kim
Hyukmin Lee
Soo Hyun Kim
Min Ji Choi
Seung A. Byun
Ga Yeong Lee
Seung-Jung Kee
Tae Yeul Kim
Mi-Na Kim
Jun Yong Choi
Dongeun Yong
Jong Hee Shin
Source :
Microbiology Spectrum.
Publication Year :
2023
Publisher :
American Society for Microbiology, 2023.

Abstract

We believe that this is the first study describe the microbiological and molecular characteristics of bloodstream isolates of C. parapsilosis in Korea exhibiting two phenotypes (sinking and floating). An important aspect of our findings is that the sinking phenotype was observed predominantly in isolates harboring a Y132F substitution in the ERG11 gene (92.9%), fluconazole-nonsusceptible (FNS) isolates (86.7%), and clonal BSI isolates (74.4%) of C. parapsilosis .

Details

ISSN :
21650497
Database :
OpenAIRE
Journal :
Microbiology Spectrum
Accession number :
edsair.doi...........4918984b47ff5b8c4b7a3383df7201f8