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The role of the C-4 side chain of kainate and dihydrokainate in EAA receptor and transporter selectivity
- Source :
- Bioorganic & Medicinal Chemistry Letters. 6:1607-1612
- Publication Year :
- 1996
- Publisher :
- Elsevier BV, 1996.
-
Abstract
- Molecular modeling was used evaluate conformational effects of side chain modifications to kainate and the pharmacological consequences of such modifications on binding to KA, NMDA, and AMPA receptors and to the high-affinity sodium-dependent glutamate transporter.
Details
- ISSN :
- 0960894X
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Accession number :
- edsair.doi...........485a8b7fe88281d83f96ff587e179151