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Molecular profiling of melanoma tumor biopsies to identify a response signature to the multi-RTK inhibitor, E7080

Authors :
N. N. Senzer
J. S. Simon
Natalie C. Twine
Tadashi Kadowaki
David S. Hong
James P. O'Brien
R. Kurzrock
A. Eisen
Min Ren
John Nemunaitis
Yasuhiro Funahashi
Source :
Journal of Clinical Oncology. 29:8595-8595
Publication Year :
2011
Publisher :
American Society of Clinical Oncology (ASCO), 2011.

Abstract

8595 Background: E7080 is an oral TKI targeting VEGFR1-3, FGFR1-4, PDGFRβ, RET and KIT, which affects tumor cell proliferation and tumor vascularization in laboratory models. Tumor response (RECIST...

Details

ISSN :
15277755 and 0732183X
Volume :
29
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........47c1df906ee8ef6a28d7aa8dc35f981b