Back to Search
Start Over
Non-peptide fibrinogen receptor antagonists. 21. The synthesis of [3H]L-738,167
- Source :
- Journal of Labelled Compounds and Radiopharmaceuticals. 41:273-277
- Publication Year :
- 1998
- Publisher :
- Wiley, 1998.
-
Abstract
- The synthesis of [3H]L-756,568, an orally active fibrinogen receptor antagonist, is described. Two synthetic pathways were developed using either bromoindoles 2a/2b or bromoaryl sufonamide 11 as the precursor. Use of the bromoaryl sulfonamide precursor led to [3H]L-756,568 with higher radiochemical purity, higher radiochemical yield, and slightly higher specific activity. Copyright © 1999 John Wiley & Sons, Ltd.
- Subjects :
- chemistry.chemical_classification
Bicyclic molecule
Fibrinogen receptor
Stereochemistry
Chemistry
Organic Chemistry
Antagonist
Fibrinogen
Biochemistry
Chemical synthesis
Analytical Chemistry
Sulfonamide
Yield (chemistry)
Drug Discovery
medicine
Radiology, Nuclear Medicine and imaging
Specific activity
Spectroscopy
medicine.drug
Subjects
Details
- ISSN :
- 03624803
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Journal of Labelled Compounds and Radiopharmaceuticals
- Accession number :
- edsair.doi...........46cceed4f98c926552e0223d5c90c0f8