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Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus

Authors :
Elham Nezhadseifi
Hourvash Ebrahimi-louyeh
Hamid Khederlou
Abdolrahman Rostamian
Source :
Rheumatology Research. 5:129-133
Publication Year :
2020
Publisher :
eJournalPlus, 2020.

Abstract

Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novelcoronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.

Details

ISSN :
24765856
Volume :
5
Database :
OpenAIRE
Journal :
Rheumatology Research
Accession number :
edsair.doi...........464b54ee5da3deab7185bbbb9b69060f