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[Untitled]
- Source :
- Journal of Inclusion Phenomena and Macrocyclic Chemistry. 42:219-226
- Publication Year :
- 2002
- Publisher :
- Springer Science and Business Media LLC, 2002.
-
Abstract
- Cyclodextrin complexation was applied to achieve better aqueous solubility of the drug and to formulate suppositories. Binary products were prepared in several mole ratios by two different methods. The dissolution profiles and in vitro membrane diffusion behaviour of the compositions were investigated. Thermoanalytical studies were performed in order to confirm inclusion complex formation. Compositions were selected for further detailed investigations and for incorporation into suppository dosage form.
Details
- ISSN :
- 09230750
- Volume :
- 42
- Database :
- OpenAIRE
- Journal :
- Journal of Inclusion Phenomena and Macrocyclic Chemistry
- Accession number :
- edsair.doi...........460211613c4be970964c6ac191ef7b8e