Determination of recommended phase II dose of ABTL0812, a novel regulator of Akt/mTOR axis, by pharmacokinetic-pharmacodynamic modelling

Authors :: Lydia Gaba
Laura Vidal
Jose M. Lizcano
Iván Victoria
J. Ramis
Berta Laquente
M. Cortal
Jose Alfon
Carles Domenech
H. Pérez-Montoyo
M. Brunet
P. Muñoz
Helena Colom
Pere Gascón
M. Gil
Tatiana Erazo
M. Gomez-Ferreria
Source :: Annals of Oncology. 27:vi120
Publication Year :: 2016
Publisher :: Elsevier BV, 2016.

Subjects :: 0301 basic medicine
medicine.medical_specialty
business.industry
Pharmacokinetic pharmacodynamic
Regulator
Hematology
Pharmacology
03 medical and health sciences
030104 developmental biology
Endocrinology
Oncology
Internal medicine
Phase (matter)
Medicine
business
Protein kinase B
PI3K/AKT/mTOR pathway

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