Host–guest binding of tetracationic cyclophanes to photodynamic agents inhibits posttreatment phototoxicity and maintains antitumour efficacy

Authors :: Jian-Da Sun
Yamin Liu
Zijian Zhao
Shang-Bo Yu
Qiao-Yan Qi
Wei Zhou
Hui Wang
Ke Hu
Dan-Wei Zhang
Zhan-Ting Li
Source :: RSC Medicinal Chemistry. 14:563-572
Publication Year :: 2023
Publisher :: Royal Society of Chemistry (RSC), 2023.
Abstract: A tetracationic macrocycle can include clinically used photodynamic agents, alleviating their posttreatment phototoxicity and maintaining their photodynamic efficacy.

Subjects :: Pharmacology
Organic Chemistry
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Biochemistry

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