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Integrated in Silico Docking and MOMA Simulation Methods Reveal Rottlerin as a Potent Janus kinase 2 (JAK2) Inhibitor
- Source :
- Biomedical Journal of Scientific & Technical Research. 11
- Publication Year :
- 2018
- Publisher :
- Biomedical Research Network, LLC, 2018.
-
Abstract
- Janus kinase 2 (JAK2) is a prospective drug target for myeloproliferative neoplasms, mainly polycythemia Vera, essential thrombocythemia and primary myelofibrosis disorders...
- Subjects :
- 0301 basic medicine
Ruxolitinib
Janus kinase 2
Tofacitinib
biology
Chemistry
Essential thrombocythemia
General Medicine
Gandotinib
medicine.disease
03 medical and health sciences
chemistry.chemical_compound
030104 developmental biology
0302 clinical medicine
Polycythemia vera
030228 respiratory system
hemic and lymphatic diseases
medicine
biology.protein
Cancer research
Myelofibrosis
Rottlerin
medicine.drug
Subjects
Details
- ISSN :
- 25741241
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Biomedical Journal of Scientific & Technical Research
- Accession number :
- edsair.doi...........43a1dd2d42980a7b7af44c9d9cdec1ee