EFFECT OF FLUORIDE VARNISH CONTAINING XYLITOL-COATED CALCIUM AND PHOSPHATE ON THE REMINERALIZATION OF CARIES LIKE LESIONS IN PRIMARY TEETH

INTRODUCTION: EmbraceTM Varnish is a new fluoride varnish which contains xylitol-coated calcium and phosphate (XCP). This combination leads to increase the release time of fluoride in this varnish.Objective: To compare the remineralizing effect of EmbraceTM varnish with Profluoride® varnish on caries-like lesions in primary teeth regarding lesion depth and calcium and phosphate enamel content.Materials and methods: Fourty eight anterior primary teeth were coated with nail varnish, leaving squares of 4x4 mm then sectioned longitudinally in a labiolingual direction into two equal halves. Each half was considered as a specimen (96 specimens). Caries-like lesions were created in all specimens. Specimens were divided into two groups. group I (n=48) was subdivided into subgroup IA (n=24) treated with EmbraceTM varnish and subgroup IB (n=24) served as control, while groupII (n=48) was subdivided into subgroup IIA (n=24) treated with Profluoride® varnish and subgroup IIB (n=24) served as control. Specimens were subjected to pH cycling then they were examined with polarized light microscopy and energy dispersive X-ray spectrometer.Results: No significant difference in mean percent reduction in lesion depth following treatment with EmbraceTM varnish and Profluoride® varnish (49.51 and 45.11, respectively) at P= 0.58. Greater significant of calcium phosphate ratio was found for EmbraceTM varnish (2.25±0.43) than Profluoride® varnish (1.65±0.05) at P< 0.0001. Significance was set at the 5% level.Conclusions: EmbraceTM varnish had no significant difference in mean percent reduction in lesion depth than Profluoride® varnish, while it had a better remineralization effect than Profluoride® varnish in terms of higher mineral content.