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In Vivo Biocompatibility of Single Walled Carbon Nanotubes
In Vivo Biocompatibility of Single Walled Carbon Nanotubes
- Source :
- ECS Meeting Abstracts. :3415-3415
- Publication Year :
- 2020
- Publisher :
- The Electrochemical Society, 2020.
-
Abstract
- Ovarian cancer patient prognosis and quality of life are significantly affected by the failure to accurately diagnose disease at early stage. Currently, less than 15% of ovarian cancer patients are diagnosed at stage 1, when 5-year survival rates are near 93%. Early detection may save more than 80% of women diagnosed with ovarian cancer. Our goal is to develop clinical long-term implantable carbon nanotube-based sensors for ovarian cancer biomarkers to transiently detect and monitor their levels in patients. The proposed sensors will harness the unique optical properties and sensitivity of single-walled carbon nanotubes. To improve sensitivity and specificity of such sensors, previously developed to detect ovarian cancer biomarkers in vivo, we used molecular perceptron—data analytics-based methods to detect specific spectroscopic fingerprints from the binding of protein biomarkers to the nanotube surface.
Details
- ISSN :
- 21512043
- Database :
- OpenAIRE
- Journal :
- ECS Meeting Abstracts
- Accession number :
- edsair.doi...........42793178846329afda0780b6f54aeb82
- Full Text :
- https://doi.org/10.1149/ma2020-02673415mtgabs