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In Vivo Biocompatibility of Single Walled Carbon Nanotubes

In Vivo Biocompatibility of Single Walled Carbon Nanotubes

Authors :
Anand Jagota
Ming Zheng
Daniel A. Heller
Zvi Yaari
Yoona Yang
Source :
ECS Meeting Abstracts. :3415-3415
Publication Year :
2020
Publisher :
The Electrochemical Society, 2020.

Abstract

Ovarian cancer patient prognosis and quality of life are significantly affected by the failure to accurately diagnose disease at early stage. Currently, less than 15% of ovarian cancer patients are diagnosed at stage 1, when 5-year survival rates are near 93%. Early detection may save more than 80% of women diagnosed with ovarian cancer. Our goal is to develop clinical long-term implantable carbon nanotube-based sensors for ovarian cancer biomarkers to transiently detect and monitor their levels in patients. The proposed sensors will harness the unique optical properties and sensitivity of single-walled carbon nanotubes. To improve sensitivity and specificity of such sensors, previously developed to detect ovarian cancer biomarkers in vivo, we used molecular perceptron—data analytics-based methods to detect specific spectroscopic fingerprints from the binding of protein biomarkers to the nanotube surface.

Details

ISSN :
21512043
Database :
OpenAIRE
Journal :
ECS Meeting Abstracts
Accession number :
edsair.doi...........42793178846329afda0780b6f54aeb82
Full Text :
https://doi.org/10.1149/ma2020-02673415mtgabs