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Abstract WP401: Burden of Intracranial Hemorrhage in Patients With Reversible Cerebral Vasoconstriction Syndrome
- Source :
- Stroke. 51
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Introduction: Reversible Cerebral Vasoconstriction Syndrome (RCVS) is described as reversible constriction of cerebral arteries, presenting with severe headaches and associated with hemorrhagic or ischemic strokes. There is a dearth of the literature on demographics and risk factors associated with intracranial hemorrhage (ICH) in patients with RCVS in the US. Methods: All patients with a primary or secondary diagnosis of RCVS in 2016 Nationwide Readmission Database (NRD) using ICD-10 code I67.841 after excluding cerebral angiitis (N=57). Unique patients were included using a unique patient identifier. Weighted discharges were used to generate national estimates. ICH was defined as both intraparenchymal and subarachnoid hemorrhage. A multivariable logistic model was used to identify ICH predictors. Results: Among total 1,152 RCVS patients, 25.7% (296) patients developed ICH. Patients with ICH mean age was (years) (Mean±SE) 47.8 ±1.2 vs. 47.0±1.1 (P=0.62), female 85.4% vs. 78.0% (P=0.06), longer inpatient LOS 12.1±0.9 vs. 6.4±0.5 days (P Conclusion: This nationally representative sample suggests that increasing age and female gender were independent predictors of ICH. There is no difference in comorbidities including migraine contrary to prior literature, modifiable lifestyle risk factors and pregnancy in this cohort. Excellent outcome was observed as the majority of patients were discharged home. Higher LOS and cost were reported in ICH cohort.
- Subjects :
- Advanced and Specialized Nursing
medicine.medical_specialty
business.industry
Cerebral arteries
medicine.disease
Reversible cerebral vasoconstriction syndrome
Constriction
Migraine
Internal medicine
medicine
Cardiology
In patient
Neurology (clinical)
Headaches
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Stroke
Subjects
Details
- ISSN :
- 15244628 and 00392499
- Volume :
- 51
- Database :
- OpenAIRE
- Journal :
- Stroke
- Accession number :
- edsair.doi...........424f8c23453ffb7490428037cdf4e7f1