ChemInform Abstract: THE REACTION OF ACETOPHENONES WITH MANGANESE(III) ACETATE

The reaction of 4′-methoxyacetophenone with manganese(III) acetate in the presence of ammonium chloride yielded 2-chloro-4′-methoxyacetophenone (2a) and 2,2-dichloro-4′-methoxyacetophenone (3a). The reaction of 2a with these reagents gave 3a, 4′-methoxy-2,2,2-trichloroacetophenone, and 1,4-bis(4-methoxyphenyl)-2,2,3,3-tetrachloro-1,4-butanedione (8a). The reactions of 2a and 2-bromoacetophenone with manganese (III) acetate yielded the corresponding 2,3-dihalo-1,4-diphenyl-1,4-butanediones, 1,4-diphenyl-2-halo-2-butene-1,4-diones, 2,3-dihalo-2-butene-1,4-diones, 2,2-dibromoacetophenone, and 8a. The reaction pathways are discussed.